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MEND Nutrition Inc.

MEND Orthopedic

$69.00 / month

With proper nutrition, the whole process of wound and tissue healing after surgery or injury can be positively impacted for better outcomes and speedier return to function. Your diet during recovery plays a crucial role in how fast your tissue heals, how strong the tissue becomes, the duration of the recovery period and how well your body fights off infection.

Poor nutrition can seriously compromise tissue healing. MEND Orthopedic was designed to support healing and recovery from orthopedic surgery, injury or the repetitive tissue stress and chronic inflammation from sports and training.

Adding MEND Orthopedic to your daily routine will provide your body with nutrients to enhance tissue strength, prevent injury, and support a healthy immune response for wounds and tissue trauma. †

from our customers


Leucine is an essential amino acid meaning it cannot be produced within the body and must be consumed. MEND contains 2.5 grams of L-Leucine per one scoop serving.


  • Leucine is one of the three branched chain amino acids (BCAAs) and is unique in its ability to stimulate skeletal muscle protein synthesis.
  • This protein synthesis means your muscles will have the ability to repair more efficiently and completely after injury, including surgery.
  • Directly activates a critical compound in muscle called the mTOR, which acts like a molecular switch to turn on the machinery that manufactures muscle proteins. These proteins will further facilitate the complete healing of trauma and injury.


Another essential amino acid which has been studied extensively. A series of cellular studies has now clearly shown that leucine directly activates a critical compound in muscle called the mTOR (mammalian target of rapamycin). It turns out mTOR is like a molecular switch that turns on the machinery that manufactures muscle proteins and leucine is one of the major activators of mTOR. So leucine not only provides the building blocks for protein synthesis, it also plays a critical role in up-regulating the process. Even when an overabundance of amino acids are available to provide the building materials for new muscle, adding extra leucine augments protein synthesis rates further. The bottom line is that adding additional leucine to your diet is an effective strategy to maximize muscle anabolism after resistance exercise.” Please see our Research section for several studies on leucine.

Glutamine is the most common amino acid found in your muscles and over 61% of skeletal muscle is Glutamine. Glutamine consists of 19% nitrogen, making it the primary transporter of nitrogen into your muscle cells. Research indicates trauma and injury can lower the levels of Glutamine to the point of deficiency. MEND contains 7.0 grams of Glutamine per one scoop serving.


  • Protein building block that facilitates metabolism and immune system.
  • After surgery or traumatic injury, nitrogen is necessary to repair the wounds and keep the vital organs functioning. A large and critical portion of this nitrogen comes from glutamine.
  • Supports human growth hormone secretion (HGH). HGH is sometimes referred to as the “youth” hormone and is a significant factor for why younger people heal more effectively.
  • A very effective intestinal and immune system health compound, as these cells use glutamine as the preferred fuel source rather than glucose.
  • Additionally, HGH plays a large role in fat metabolism and muscle growth.


According to NYU Lagone Medical Center “Heavy exercise, infection, surgery, and trauma can deplete the body’s glutamine reserves, particularly in muscle cells. The fact that glutamine does so many good things in the body has led people to research glutamine supplements as a treatment for various conditions, including preventing the infections that often follow endurance exercise, reducing symptoms of overtraining syndrome, improving nutrition in critical illness, alleviating allergies, and treating digestive problems.”Please read Nutrition in Clinical Practice’s “Clinical applications of Glutamine”.

HMB is a metabolite of the essential amino acid Leucine and is synthesized in the human body. It plays a part in protein synthesis. MEND contains 1.5 grams of HMB per one scoop serving.


  • Studies now indicate HMB inhibits protein degradation in the body, which promotes muscle growth, and prevents muscle breakdown.
  • HMB appears to be the main metabolite of leucine that more effectively prevents the breakdown of muscle protein.
  • A review article, published in January 2008 in the “Nutrition & Metabolism” journal, indicates that multiple studies found that HMB had positive effects on strength, lean body composition and reduced soreness on trained athletes.
  • HMB helps speed up muscle repair and recovery time


Numerous studies have found increases in lean muscle mass and strength in the elderly and clinical populations when using HMB. Our research section contains papers as well as a link to PubMed which can be used to look up the studies on HMB. Please read “International Society of Sports Medicine Postion on HBM.”

Whey protein comes from cow’s milk and is a rich source of the body’s essential amino acids. Our Whey is grass fed and 100% antibiotic and hormone free. Whey protein isolate is the most pure form (it contains greater than 90% protein) and it has little to no fat, lactose or cholesterol. MEND contains 7.5 grams of Whey Isolate Protein per one scoop serving.


  • Protein is one of the body’s main building blocks for muscle, bone, skin, and other tissues.
  • Whey protein has the unique ability to enhance the absorption of nutrients. This is thought to be accomplished by its ability to increase cell sensitivity by improving insulin sensitivity.
  • Recent research indicates whey protein accelerates the ability of your body to generate glutathione, a powerful antioxidant that protects and rejuvenates cell tissue.
  • Additional research shows a significant reduction in inflammation post-injury, as compared to ” sulfasalazin” a commonly prescribed anti-inflammatory drug.


Strong scientific evidence, rated A by Mayo Clinic: “Whey protein has been studied for maintaining skeletal muscle mass. Studies suggest that whey protein may benefit older people and women after exercise. In healthy young men, whey protein increased blood levels of essential amino acids and the creation of muscle protein. Whey protein is considered by experts to be an excellent source of protein.”

Turmeric is a plant of the ginger family and is quickly becoming one of the most studied and important herbs for healing and health known today. MEND contains 300 milligrams of Turmeric per one scoop serving


  • A potent, yet safe anti-inflammatory that facilitates healing.
  • Contains six different COX-2-inhibitors (the COX-2 enzyme promotes pain, swelling and inflammation; inhibitors selectively block that enzyme).


Now one of the most studied natural herbs, which has been studied for everything from inflammation to infections to arthritis. Strong evidence for a variety of benefits including the anti-inflammatory benefits.

BioPerine® is a patented extract obtained from black pepper fruits (Piper nigrum) standardized minimum to 95% Piperine and has been used as a bioavailability enhancer for more than 20 years. BioPerine® is commonly administered together with Turmeric to enhance absorption and efficacy.


  • Increase bioavailability and absorption of nutrients. Used in MEND primarily to enhance efficacy of Turmeric.
  • There is some evidence that BioPerine may reduce inflammation and help to regulate a healthy immune response.


A number of clinical studies have evaluated BioPerine with a variety of nutrient groups. Clinical information can be found on the BioPerine site below.

itamin A is a fat soluble vitamin which is present in many foods. Two different types of vitamin A are found in the diet. Preformed vitamin A is found in animal products such as meat, fish, poultry and dairy foods. The other type, pro-vitamin A is found in plant-based foods such as fruits and vegetables. MEND contains 1250 IU of Vitamin A per one scoop serving.


  • Vitamin A is required for epithelial and bone formation, cellular differentiation and immune function. It therefore plays a significant role in wound healing and bone healing/rebuilding.
  • Most cartenoid forms of vitamin A function as antioxidant and anti-inflammatory nutrients


According to National Institute of Health: “Vitamin A is essential for good health. It promotes growth, the immune system, reproduction, and vision. However, recent research suggests that too much vitamin A, particularly in the form of retinol, may be bad for your bones.” Please refer to the NIH Osteoporosis and Related Bone Diseases site for more information on studies and recommended intake.

Vitamin C is a water soluble nutrient found in some foods. Because of the additional free radical damage typically occurring with injury, vitamin C can be consumed by the body quickly during the healing process. MEND contains 250 milligrams of Vitamin C per one scoop serving.


  • Known as a strong antioxidant, vitamin C can help neutralize the free radicals associated with trauma and injury.
  • Aids in building connective tissue.
  • Aids in wound healing.


According to PubMed: “Clinical studies provide evidence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA).” According to another study on Vitamin C as an antioxidant: “Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this property accounts for all its known functions. As an electron donor, vitamin C is a potent water-soluble antioxidant in humans. Antioxidant effects of vitamin C have been demonstrated in many experiments in vitro.” According to Dr. Sinatra: Because surgery depletes your body of vitamin C, take 500–1,000 mg as part of your daily routine before surgery and 1,000 mg three times a day after surgery. Return to your usual dosage after two weeks. Numerous studies indicate that vitamin C helps prevent surgical shock and post-surgical bed sores, and that it significantly speeds healing time. It’s also necessary for the production of collagen—a basic structural protein used in wound repair.

Vitamin D is an essential vitamin which the body produces in exposure to sunlight. It can be found in few foods naturally. MEND contains 400 IU of Vitamin D per one scoop serving.


  • Crucial for absorption of calcium and bone health. The Vitamin D will help aid the absorption of the Calcium contained in MEND.
  • Aids and regulates the immune system.


Vitamin D has become one of the most researched and prescribed vitamins. Conclusions according to one study: “This meta-analysis supports the use of vitamin D3 of 800 IU daily to reduce the incidence of osteoporotic non-vertebral, hip, and non-vertebral-non-hip fractures in elderly women. Vitamin D(3) with calcium appears to achieve benefits above those attained with calcium supplementation alone for non-vertebral and non-vertebral-non-hip fractures.”

Zinc is an essential mineral found in many foods. MEND contains 7.0 milligrams of Zinc per one scoop serving.


  • Aids in wound healing.
  • Needed to activate T Cells which help the body to control and regulate the immune response.


According to Nutrition in Clinical Practicel: The role of nutrition in wound healing is well documented. Malnourished individuals demonstrate impaired wound healing. Specific nutrients are known to be essential in the wound-healing process. Zinc, a component of multiple enzymes, is important in the formation of collagen, a critical component in the healing wound. The practice of providing supplemental zinc to patients with wounds is not uncommon

Additional Research:

Boron is a mineral that is found in foods such as nuts. Boron is used for building strong bones, treating osteoarthritis, as an aid for building muscles and increasing testosterone levels, and for improving thinking skills and muscle coordination. Boron is also beneficial in wound healing.


  • Aids and speeds up wound healing.
  • Effective at reducing certain inflammatory markers.


There have been a number of clinical studies done on boron for a wide variety of uses. For example a 1990 clinical study on wound healing showed that boron was able to reduce the healing time by two thirds (source: link).

Calcium is a mineral found in many foods. MEND contains 50 milligrams of Calcium per one scoop serving.


  • An essential nutrient to build, maintain and restore bones during the healing process.
  • Recent studies show that a flash of calcium is the body’s first immune response to healing tissue.
  • Plays a critical role in nerve function, muscle movement and to carrying messages from the brain to the rest of the body, all of which are critical for the healing process.
  • Helps move blood throughout the body and to help release important hormones and enzymes, important in the healing process.


The findings of a 2013 study, published in Current Biology, shows that a flash of calcium is the body’s first response to healing damaged tissue. The study can be found in our research section.

According to Medscape: “Calcium plus vitamin D supplements are routinely prescribed for the prevention of osteoporosis and fracture. Although a major study from 2006 questioned this practice, a new meta-analysis reaffirms the usefulness of calcium plus vitamin D in the prevention of fracture.”

About 70% of iron in one’s body is found in hemoglobin and myoglobin. Hemoglobin is the primary transporter of oxygen from the lungs to the body’s tissues, while myoglobin is in muscle cells, and makes acceptance, storage, transportation, and release of oxygen possible in those cells. About 5% of iron is found as components of various proteins and as necessary elements in certain enzymatic reactions. Up to 25% of the body’s iron is stored in ferritin, which is in the cells and circulating in the bloodstream. Ferritin can store up to three years’ worth of iron supplementation for men, but only about one year’s worth for women, which is why anemia is more common in females.


  • The main health benefit of a diet high in iron is the formation of hemoglobin. Hemoglobin is the principal carrier of oxygen throughout the body and gives the dark red color to blood.
  • One of the most important health benefits of iron is that it acts as a carrier of oxygen and helps transfer oxygen from one body cell to another. This is a critical function of iron as oxygen is required by each and every body part to perform routine body functions.
  • Iron is a vital element for muscle health and is found in myoglobin, a muscle protein. Myoglobin carries oxygen from hemoglobin and diffuses it throughout muscle cells. This is required for contraction of muscles.


Very commonly studied for anemia and iron deficiency with proven efficacy of supplementation. More study required on benefits of supplementation to injured or post surgery population.


Where can I buy MEND Orthopedic?

MEND is available through your doctor or surgeon and can be purchased directly from our website.

Can you ship to my country?

Yes, MEND is shipped worldwide. Please be aware of your country’s policy for importing dietary supplements and that additional taxes and tariffs may be applied by your country.

What flavors are available?

MEND Orthopedic is available in citrus flavor. The NSF Sport certified may be taken by professional athletes and therefore is a little bit more expensive. They are the same product, however, and may be taken interchangeably.

Is MEND safe to be taken before surgery?

MEND Orthopedic contains only well-studied, well-tolerated nutrients that are safe and may be taken before and after surgery. It is always advisable to check with your doctor before taking any dietary supplements.†

Does MEND contain natural flavors and sweeteners?

MEND contains 100% natural flavors and sweeteners, and is non-GMO and Gluten free

Is MEND Orthopedic proven to work?

All of the nutrients in MEND Orthopedic were selected based on the science and evidence supporting their efficacy. We now have more than 3 years of patient data and numerous testimonials suggesting that MEND is efficacious.†